Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50193282
Substrate
n/a
Meas. Tech.
ChEBML_1615641
Ki
52±n/a nM
Citation
 Lazzari, P; Distinto, R; Manca, I; Baillie, G; Murineddu, G; Pira, M; Falzoi, M; Sani, M; Morales, P; Ross, R; Zanda, M; Jagerovic, N; Pinna, GA A critical review of both the synthesis approach and the receptor profile of the 8-chloro-1-(2',4'-dichlorophenyl)-N-piperidin-1-yl-1,4,5,6-tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide and analogue derivatives. Eur J Med Chem 121:194-208 (2016) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50193282
Synonyms:
CHEMBL3949933
Type:
Small organic molecule
Emp. Form.:
C24H22Cl3N3O2
Mol. Mass.:
490.809
SMILES:
Clc1ccc(c(Cl)c1)-n1nc(C(=O)NC[C@H]2CCCO2)c2CCCc3cc(Cl)ccc3-c12 |r|
Structure:
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