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Target
Mu-type opioid receptor
Ligand
BDBM50194236
Substrate
n/a
Meas. Tech.
ChEMBL_1616610 (CHEMBL3858679)
Ki
1750±n/a nM
Citation
 Guerrieri, E; Bermudez, M; Wolber, G; Berzetei-Gurske, IP; Schmidhammer, H; Spetea, M Structural determinants of diphenethylamines for interaction with theż opioid receptor: Synthesis, pharmacology and molecular modeling studies. Bioorg Med Chem Lett 26:4769-4774 (2016) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50194236
Synonyms:
CHEMBL3950863
Type:
Small organic molecule
Emp. Form.:
C20H25NO
Mol. Mass.:
295.4186
SMILES:
Oc1ccc(CCN(CCc2ccccc2)CC2CC2)cc1
Structure:
Search PDB for entries with ligand similarity: