Reaction Details Report a problem with these data
Target
Kappa-type opioid receptor
Ligand
BDBM50194236
Substrate
n/a
Meas. Tech.
ChEMBL_1616609 (CHEMBL3858678)
Ki
218±n/a nM
Citation
 Guerrieri, E; Bermudez, M; Wolber, G; Berzetei-Gurske, IP; Schmidhammer, H; Spetea, M Structural determinants of diphenethylamines for interaction with theż opioid receptor: Synthesis, pharmacology and molecular modeling studies. Bioorg Med Chem Lett 26:4769-4774 (2016) [PubMed]  Article 
Target
Name:
Kappa-type opioid receptor
Synonyms:
K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42648.76
Organism:
Homo sapiens (Human)
Description:
P41145
Residue:
380
Sequence:
MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRVRNTVQDPAYLRDIDGMNKPV
  
Inhibitor
Name:
BDBM50194236
Synonyms:
CHEMBL3950863
Type:
Small organic molecule
Emp. Form.:
C20H25NO
Mol. Mass.:
295.4186
SMILES:
Oc1ccc(CCN(CCc2ccccc2)CC2CC2)cc1
Structure:
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