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Target
Amine oxidase [flavin-containing] B
Ligand
BDBM50194552
Substrate
n/a
Meas. Tech.
ChEMBL_1616766 (CHEMBL3858835)
IC50
2420±n/a nM
Citation
 Nel, MS; Petzer, A; Petzer, JP; Legoabe, LJ 2-Benzylidene-1-indanone derivatives as inhibitors of monoamine oxidase. Bioorg Med Chem Lett 26:4599-4605 (2016) [PubMed]  Article 
Target
Name:
Amine oxidase [flavin-containing] B
Synonyms:
AOFB_HUMAN | MAO-B | MAOB | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB)
Type:
Protein
Mol. Mass.:
58768.76
Organism:
Homo sapiens (Human)
Description:
P27338
Residue:
520
Sequence:
MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
  
Inhibitor
Name:
BDBM50194552
Synonyms:
CHEMBL3925000
Type:
Small organic molecule
Emp. Form.:
C16H12O2
Mol. Mass.:
236.2653
SMILES:
Oc1ccc2C\C(=C/c3ccccc3)C(=O)c2c1
Structure:
Search PDB for entries with ligand similarity: