Reaction Details Report a problem with these data
Target
Beta-lactamase
Ligand
BDBM50000407
Substrate
n/a
Meas. Tech.
ChEMBL_1617949 (CHEMBL3860118)
Kd
>1000000±n/a nM
Citation
 Lund, BA; Christopeit, T; Guttormsen, Y; Bayer, A; Leiros, HK Screening and Design of Inhibitor Scaffolds for the Antibiotic Resistance Oxacillinase-48 (OXA-48) through Surface Plasmon Resonance Screening. J Med Chem 59:5542-54 (2016) [PubMed]  Article 
Target
Name:
Beta-lactamase
Synonyms:
Beta-lactamase | OXA-48 | Synonyms=blaOXA-48 | bla
Type:
PROTEIN
Mol. Mass.:
30363.94
Organism:
Klebsiella pneumoniae
Description:
ChEMBL_103606
Residue:
265
Sequence:
MRVLALSAVFLVASIIGMPAVAKEWQENKSWNAHFTEHKSQGVVVLWNENKQQGFTNNLKRANQAFLPASTFKIPNSLIALDLGVVKDEHQVFKWDGQTRDIATWNRDHNLITAMKYSVVPVYQEFARQIGEARMSKMLHAFDYGNEDISGNVDSFWLDGGIRISATEQISFLRKLYHNKLHVSERSQRIVKQAMLTEANGDYIIRAKTGYSTRIEPKIGWWVGWVELDDNVWFFAMNMDMPTSDGLGLRQAITKEVLKQEKIIP
  
Inhibitor
Name:
BDBM50000407
Synonyms:
2-carboxypyridine | CHEMBL72628 | alpha-picolinic acid | alpha-pyridinecarboxylic acid | o-pyridinecarboxylic acid | picolinic acid | pyridine-2-carboxylic acid
Type:
Small organic molecule
Emp. Form.:
C6H5NO2
Mol. Mass.:
123.1094
SMILES:
OC(=O)c1ccccn1
Structure:
Search PDB for entries with ligand similarity: