Reaction Details Report a problem with these data
Target
Free fatty acid receptor 4
Ligand
BDBM50196403
Substrate
n/a
Meas. Tech.
ChEMBL_1618417 (CHEMBL3860586)
EC50
16596±n/a nM
Citation
 Azevedo, CM; Watterson, KR; Wargent, ET; Hansen, SV; Hudson, BD; Kepczynska, MA; Dunlop, J; Shimpukade, B; Christiansen, E; Milligan, G; Stocker, CJ; Ulven, T Non-Acidic Free Fatty Acid Receptor 4 Agonists with Antidiabetic Activity. J Med Chem 59:8868-8878 (2016) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 4
Synonyms:
FFAR4 | FFAR4_HUMAN | G-protein coupled receptor 120 | G-protein coupled receptor 129 | G-protein coupled receptor GT01 | G-protein coupled receptor PGR4 | GPR120 | GPR129 | O3FAR1 | Omega-3 fatty acid receptor 1 | PGR4
Type:
PROTEIN
Mol. Mass.:
42256.91
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1508994
Residue:
377
Sequence:
MSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVCALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILYNMTLCRNEWKKIFCCFWFPEKGAILTDTSVKRNDLSIISG
  
Inhibitor
Name:
BDBM50196403
Synonyms:
CHEMBL3961620
Type:
Small organic molecule
Emp. Form.:
C17H12F2N2O3S
Mol. Mass.:
362.351
SMILES:
Fc1ccc(cc1)S(=O)(=O)Nc1cc(F)cc(Oc2cccnc2)c1
Structure:
Search PDB for entries with ligand similarity: