Reaction Details Report a problem with these data
Target
Free fatty acid receptor 1
Ligand
BDBM50196404
Substrate
n/a
Meas. Tech.
ChEMBL_1618421 (CHEMBL3860590)
IC50
12882±n/a nM
Citation
 Azevedo, CM; Watterson, KR; Wargent, ET; Hansen, SV; Hudson, BD; Kepczynska, MA; Dunlop, J; Shimpukade, B; Christiansen, E; Milligan, G; Stocker, CJ; Ulven, T Non-Acidic Free Fatty Acid Receptor 4 Agonists with Antidiabetic Activity. J Med Chem 59:8868-8878 (2016) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 1
Synonyms:
FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
31473.32
Organism:
Homo sapiens (Human)
Description:
O14842
Residue:
300
Sequence:
MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAGPARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
  
Inhibitor
Name:
BDBM50196404
Synonyms:
CHEMBL3894632
Type:
Small organic molecule
Emp. Form.:
C18H14FNO3S
Mol. Mass.:
343.372
SMILES:
Fc1ccc(cc1)S(=O)(=O)Nc1ccc(Oc2ccccc2)cc1
Structure:
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