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Target
Free fatty acid receptor 4
Ligand
BDBM50207075
Substrate
n/a
Meas. Tech.
ChEMBL_1629515 (CHEMBL3872141)
EC50
18±n/a nM
Citation
 Adams, GL; Velazquez, F; Jayne, C; Shah, U; Miao, S; Ashley, ER; Madeira, M; Akiyama, TE; Di Salvo, J; Suzuki, T; Wang, N; Truong, Q; Gilbert, E; Zhou, D; Verras, A; Kirkland, M; Pachanski, M; Powles, M; Yin, W; Ujjainwalla, F; Venkatraman, S; Edmondson, SD Discovery of Chromane Propionic Acid Analogues as Selective Agonists of GPR120 with ACS Med Chem Lett 8:96-101 (2017) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 4
Synonyms:
FFAR4 | FFAR4_HUMAN | G-protein coupled receptor 120 | G-protein coupled receptor 129 | G-protein coupled receptor GT01 | G-protein coupled receptor PGR4 | GPR120 | GPR129 | O3FAR1 | Omega-3 fatty acid receptor 1 | PGR4
Type:
PROTEIN
Mol. Mass.:
42256.91
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1508994
Residue:
377
Sequence:
MSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVCALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILYNMTLCRNEWKKIFCCFWFPEKGAILTDTSVKRNDLSIISG
  
Inhibitor
Name:
BDBM50207075
Synonyms:
CHEMBL3898962
Type:
Small organic molecule
Emp. Form.:
C23H24FNO5
Mol. Mass.:
413.4388
SMILES:
[H][C@]1(C[C@@]1([H])[C@@]1([H])CCc2cc(ccc2O1)-c1nc(OC2CCC2)cc(OC)c1F)C(O)=O |r|
Structure:
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