Reaction Details Report a problem with these data
Target
NAD kinase
Ligand
BDBM50208734
Substrate
n/a
Meas. Tech.
ChEMBL_1633194 (CHEMBL3875986)
IC50
>400000±n/a nM
Citation
 Paoletti, J; Assairi, L; Gelin, M; Huteau, V; Nahori, MA; Dussurget, O; Labesse, G; Pochet, S 8-Thioalkyl-adenosine derivatives inhibit Listeria monocytogenes NAD kinase through a novel binding mode. Eur J Med Chem 124:1041-1056 (2016) [PubMed]  Article 
Target
Name:
NAD kinase
Synonyms:
NAD kinase (NADK) | NADK_STAAC | nadK
Type:
Protein
Mol. Mass.:
30776.91
Organism:
Staphylococcus aureus
Description:
Q5HH78
Residue:
269
Sequence:
MRYTILTKGDSKSNALKHKMMNYMKDFRMIEDSENPEIVISVGGDGTLLQAFHQYSHMLSKVAFVGVHTGHLGFYADWLPHEVEKLIIEINNSEFQVIEYPLLEIIMRYNDNGYETRYLALNEATMKTENGSTLVVDVNLRGKHFERFRGDGLCVSTPSGSTAYNKALGGALIHPSLEAMQITEIASINNRVFRTVGSPLVLPKHHTCLISPVNHDTIRMTIDHVSIKHKNVNSIQYRVANEKVRFARFRPFPFWKRVHDSFISSDEER
  
Inhibitor
Name:
BDBM50208734
Synonyms:
CHEMBL3883980
Type:
Small organic molecule
Emp. Form.:
C20H23BrN6O5S
Mol. Mass.:
539.403
SMILES:
Nc1ncnc2n([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c(SCC(=O)NCCc3cccc(Br)c3)nc12 |r|
Structure:
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