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Target
Metallo-beta-lactamase type 2
Ligand
BDBM50212635
Substrate
n/a
Meas. Tech.
ChEMBL_40251 (CHEMBL855016)
IC50
40.6±n/a nM
Citation
  TBA Bioorg Med Chem Lett 3:2247-2252 (1993)   
Target
Name:
Metallo-beta-lactamase type 2
Synonyms:
BLAB_BACFG | Beta-lactamase type II | ccrA | cfiA
Type:
PROTEIN
Mol. Mass.:
27252.87
Organism:
Bacteroides fragilis
Description:
ChEMBL_1502123
Residue:
249
Sequence:
MKTVFILISMLFPVAVMAQKSVKISDDISITQLSDKVYTYVSLAEIEGWGMVPSNGMIVINNHQAALLDTPINDAQTEMLVNWVTDSLHAKVTTFIPNHWHGDCIGGLGYLQRKGVQSYANQMTIDLAKEKGLPVPEHGFTDSLTVSLDGMPLQCYYLGGGHATDNIVVWLPTENILFGGCMLKDNQATSIGNISDADVTAWPKTLDKVKAKFPSARYVVPGHGDYGGTELIEHTKQIVNQYIESTSKP
  
Inhibitor
Name:
BDBM50212635
Synonyms:
CHEMBL415266
Type:
Small organic molecule
Emp. Form.:
C10H12BrN5O3S2
Mol. Mass.:
394.268
SMILES:
[H][C@]12S[C@@](C)(CSc3nnnn3C)[C@@H](N1C(=O)[C@H]2Br)C(O)=O
Structure:
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