Reaction Details Report a problem with these data
Target
Beta-lactamase OXA-1
Ligand
BDBM50212640
Substrate
n/a
Meas. Tech.
ChEMBL_40708 (CHEMBL654920)
IC50
375±n/a nM
Citation
  TBA Bioorg Med Chem Lett 3:2247-2252 (1993)   
Target
Name:
Beta-lactamase OXA-1
Synonyms:
BLO1_ECOLX | Beta-lactamase OXA-1 | Class D β-lactamase (OXA-1) | bla | oxa1
Type:
Enzyme
Mol. Mass.:
30882.83
Organism:
Escherichia coli (Enterobacteria)
Description:
Q83ZU9
Residue:
276
Sequence:
MKNTIHINFAIFLIIANIIYSSASASTDISTVASPLFEGTEGCFLLYDASTNAEIAQFNKAKCATQMAPDSTFKIALSLMAFDAEIIDQKTIFKWDKTPKGMEIWNSNHTPKTWMQFSVVWVSQEITQKIGLNKIKNYLKDFDYGNQDFSGDKERNNGLTEAWLESSLKISPEEQIQFLRKIINHNLPVKNSAIENTIENMYLQDLDNSTKLYGKTGAGFTANRTLQNGWFEGFIISKSGHKYVFVSALTGNLGSNLTSSIKAKKNAITILNTLNL
  
Inhibitor
Name:
BDBM50212640
Synonyms:
CHEMBL423309
Type:
Small organic molecule
Emp. Form.:
C11H14N4O5S2
Mol. Mass.:
346.383
SMILES:
[H][C@@]12CC(=O)N1[C@@H](C(O)=O)[C@](C)(CSc1nncn1C)S2(=O)=O
Structure:
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