Reaction Details Report a problem with these data
Target
Cholecystokinin receptor type A
Ligand
BDBM50214808
Substrate
n/a
Meas. Tech.
ChEMBL_49902 (CHEMBL665890)
Ki
79±n/a nM
Citation
  TBA Bioorg Med Chem Lett 7:281-286 (1997)   
Target
Name:
Cholecystokinin receptor type A
Synonyms:
CCK-A receptor | CCK-AR | CCK1-R | CCKAR | CCKAR_HUMAN | CCKRA | Cholecystokinin receptor | Cholecystokinin receptor type A | Cholecystokinin-1 Receptor
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
47859.34
Organism:
Homo sapiens (Human)
Description:
Stable expression of human CCK-1 receptors in HEK 293 cells.
Residue:
428
Sequence:
MDVVDSLLVNGSNITPPCELGLENETLFCLDQPRPSKEWQPAVQILLYSLIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICKPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPNDVMQQSWHTFLLLILFLIPGIVMMVAYGLISLELYQGIKFEASQKKSAKERKPSTTSSGKYEDSDGCYLQKTRPPRKLELRQLSTGSSSRANRIRSNSSAANLMAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTASAERRLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGARGEVGEEEEGGTTGASLSRFSYSHMSASVPPQ
  
Inhibitor
Name:
BDBM50214808
Synonyms:
CHEMBL320141 | GR-199114X
Type:
Small organic molecule
Emp. Form.:
C28H32FN5O4
Mol. Mass.:
521.5832
SMILES:
Fc1ccc(NC(=O)N[C@H]2C(=O)N(CC(=O)N3CCCC3)c3ccccc3N(C3CCCCC3)C2=O)cc1
Structure:
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