Reaction Details Report a problem with these data
Target
D(3) dopamine receptor
Ligand
BDBM50369174
Substrate
n/a
Meas. Tech.
ChEBML_62601
Ki
25±n/a nM
Citation
 Avenell, KY; Boyfield, I; Hadley, MS; Johnson, CN; Nash, DJ; Riley, GJ; Stemp, G Heterocyclic analogues of 2-aminotetralins with high affinity and selectivity for the dopamine D3 receptor. Bioorg Med Chem Lett 9:2715-20 (1999) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50369174
Synonyms:
CHEMBL94015 | PD-128907
Type:
Small organic molecule
Emp. Form.:
C14H19NO3
Mol. Mass.:
249.3056
SMILES:
CCCN1COC[C@H]2[C@H]1COc1ccc(O)cc21
Structure:
Search PDB for entries with ligand similarity: