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Target
Cholesterol side-chain cleavage enzyme, mitochondrial
Ligand
BDBM50225959
Substrate
n/a
Meas. Tech.
ChEMBL_206368 (CHEMBL813258)
IC50
401±n/a nM
Citation
 Lejczak, B; Kafarski, P; Sztajer, H; Mastalerz, P Antibacterial activity of phosphono dipeptides related to alafosfalin. J Med Chem 29:2212-7 (1986) [PubMed]  Article 
Target
Name:
Cholesterol side-chain cleavage enzyme, mitochondrial
Synonyms:
CP11A_RAT | Cyp11a | Cyp11a-1 | Cyp11a1 | Cytochrome P450 11A1
Type:
PROTEIN
Mol. Mass.:
60603.33
Organism:
Rattus norvegicus
Description:
ChEMBL_50353
Residue:
526
Sequence:
MLAKGLCLRSVLVKSCQPFLSPVWQGPGLATGNGAGISSTNSPRSFNEIPSPGDNGWINLYHFLRENGTHRIHYHHMQNFQKYGPIYREKLGNMESVYILDPKDAATLFSCEGPNPERYLVPPWVAYHQYYQRPIGVLFKSSDAWRKDRIVLNQEVMAPDSIKNFVPLLEGVAQDFIKVLHRRIKQQNSGKFSGDISDDLFRFAFESITSVVFGERLGMLEEIVDPESQRFIDAVYQMFHTSVPMLNMPPDLFRLFRTKTWKDHAAAWDVIFSKADEYTQNFYWDLRQKRDFSKYPGVLYSLLGGNKLPFKNIQANITEMLAGGVDTTSMTLQWNLYEMAHNLKVQEMLRAEVLAARRQAQGDMAKMVQLVPLLKASIKETLRLHPISVTLQRYIVNDLVLRNYKIPAKTLVQVASYAMGRESSFFPNPNKFDPTRWLEKSQNTTHFRYLGFGWGVRQCLGRRIAELEMTIFLINVLENFRIEVQSIRDVGTKFNLILMPEKPIFFNFQPLKQDLGSTMPRKGDTV
  
Inhibitor
Name:
BDBM50225959
Synonyms:
CHEMBL307316
Type:
Small organic molecule
Emp. Form.:
C7H17N2O4P
Mol. Mass.:
224.1946
SMILES:
CC(C)C(NC(=O)C(C)N)P(O)(O)=O
Structure:
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