Reaction Details Report a problem with these data
Target
Similar to alpha-tubulin isoform 1
Ligand
BDBM50009565
Substrate
n/a
Meas. Tech.
ChEMBL_39798 (CHEMBL876771)
IC50
3400±n/a nM
Citation
 Cushman, M; Nagarathnam, D; Gopal, D; Chakraborti, AK; Lin, CM; Hamel, E Synthesis and evaluation of stilbene and dihydrostilbene derivatives as potential anticancer agents that inhibit tubulin polymerization. J Med Chem 34:2579-88 (1991) [PubMed]  Article 
Target
Name:
Similar to alpha-tubulin isoform 1
Synonyms:
Similar to alpha-tubulin isoform 1
Type:
PROTEIN
Mol. Mass.:
10383.05
Organism:
Bos taurus
Description:
ChEMBL_104716
Residue:
99
Sequence:
CVSASPSTLARLVSRSAMPAGSSTAWNTAFSPMARCQVTKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRSSSTLSSSSQAKKMP
  
Inhibitor
Name:
BDBM50009565
Synonyms:
CHEMBL312992 | Dimethyl-{4-[(Z)-2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenyl}-amine | Dimethyl-{4-[2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenyl}-amine
Type:
Small organic molecule
Emp. Form.:
C19H23NO3
Mol. Mass.:
313.3908
SMILES:
COc1cc(\C=C/c2ccc(cc2)N(C)C)cc(OC)c1OC
Structure:
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