Reaction Details Report a problem with these data
Target
Adenosine receptor A2a
Ligand
BDBM50231590
Substrate
n/a
Meas. Tech.
ChEMBL_1645469 (CHEMBL3994398)
Ki
2000±n/a nM
Citation
 Koul, S; Ramdas, V; Barawkar, DA; Waman, YB; Prasad, N; Madadi, SK; Shejul, YD; Bonagiri, R; Basu, S; Menon, S; Reddy, SB; Chaturvedi, S; Chennamaneni, SR; Bedse, G; Thakare, R; Gundu, J; Chaudhary, S; De, S; Meru, AV; Palle, V; Chugh, A; Mookhtiar, KA Design and synthesis of novel, potent and selective hypoxanthine analogs as adenosine A Bioorg Med Chem 25:1963-1975 (2017) [PubMed]  Article 
Target
Name:
Adenosine receptor A2a
Synonyms:
A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44716.46
Organism:
Homo sapiens (Human)
Description:
P29274
Residue:
412
Sequence:
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
  
Inhibitor
Name:
BDBM50231590
Synonyms:
CHEMBL4063997
Type:
Small organic molecule
Emp. Form.:
C19H23N5O2
Mol. Mass.:
353.4182
SMILES:
CCCn1c(Oc2cccnc2C)nc2nc([nH]c2c1=O)C1CCCC1
Structure:
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