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Target
G-protein coupled receptor 39
Ligand
BDBM50232401
Substrate
n/a
Meas. Tech.
ChEMBL_1646465 (CHEMBL3995521)
EC50
5.0±n/a nM
Citation
 Frimurer, TM; Mende, F; Graae, AS; Engelstoft, MS; Egerod, KL; Nygaard, R; Gerlach, LO; Hansen, JB; Schwartz, TW; Holst, B Model-Based Discovery of Synthetic Agonists for the Zn J Med Chem 60:886-898 (2017) [PubMed]  Article 
Target
Name:
G-protein coupled receptor 39
Synonyms:
G-protein coupled receptor 39 | GPR39_MOUSE | Gpr39
Type:
PROTEIN
Mol. Mass.:
51615.79
Organism:
Mus musculus
Description:
ChEMBL_109498
Residue:
456
Sequence:
MASSSGSNHICSRVIDHSHVPEFEVATWIKITLILVYLIIFVVGILGNSVTIRVTQVLQKKGYLQKEVTDHMVSLACSDILVFLIGMPMEFYSIIWNPLTTPSYALSCKLHTFLFETCSYATLLHVLTLSFERYIAICHPFKYKAVSGPRQVKLLIGFVWVTSALVALPLLFAMGIEYPLVNVPTHKGLNCNLSRTRHHDEPGNSNMSICTNLSNRWEVFQSSIFGAFAVYLVVLASVAFMCWNMMKVLMKSKQGTLAGTGPQLQLRKSESEESRTARRQTIIFLRLIVVTLAVCWMPNQIRRIMAAAKPKHDWTRTYFRAYMILLPFSDTFFYLSSVVNPLLYNVSSQQFRKVFWQVLCCRLTLQHANQEKRQRARFISTKDSTSSARSPLIFLASRRSNSSSRRTNKVFLSTFQTEAKPGEAKPQPLSPESPQTGSETKPAGSTTENSLQEQEV
  
Inhibitor
Name:
BDBM50232401
Synonyms:
CHEMBL4077818
Type:
Small organic molecule
Emp. Form.:
C18H13ClFN7O
Mol. Mass.:
397.794
SMILES:
Cc1nn(c2NC(=O)CC(c12)c1ccc(F)cc1Cl)-c1ncnc2nc[nH]c12
Structure:
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