Target
5-hydroxytryptamine receptor 7
Ligand
BDBM50232670
Substrate
n/a
Meas. Tech.
ChEMBL_1648451 (CHEMBL3997507)
Ki
>10000±n/a nM
Citation
 Staron, JMordalski, SWarszycki, DSatala, GHogendorf, ABojarski, AJ Pyrano[2,3,4- ACS Med Chem Lett 8:390-394 (2017) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 7
Synonyms:
5-HT-7 | 5-HT-X | 5-HT7 | 5-HT7L | 5-HT7S | 5-HT7b | 5HT7 | 5HT7R_HUMAN | HTR7 | Serotonin receptor 7
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
53573.08
Organism:
Homo sapiens (Human)
Description:
P34969
Residue:
479
Sequence:
MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTWDAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALKLAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD
  
Inhibitor
Name:
BDBM50232670
Synonyms:
CHEMBL4088416
Type:
Small organic molecule
Emp. Form.:
C17H13NO4S
Mol. Mass.:
327.354
SMILES:
OCc1cc2cn(c3cccc(o1)c23)S(=O)(=O)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: