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Target
Cannabinoid receptor 1
Ligand
BDBM50232934
Substrate
n/a
Meas. Tech.
ChEMBL_1649598 (CHEMBL3998732)
Ki
365±n/a nM
Citation
 Ragusa, G; Gómez-Cañas, M; Morales, P; Rodríguez-Cueto, C; Pazos, MR; Asproni, B; Cichero, E; Fossa, P; Pinna, GA; Jagerovic, N; Fernández-Ruiz, J; Murineddu, G New pyridazinone-4-carboxamides as new cannabinoid receptor type-2 inverse agonists: Synthesis, pharmacological data and molecular docking. Eur J Med Chem 127:398-412 (2017) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50232934
Synonyms:
CHEMBL4098746
Type:
Small organic molecule
Emp. Form.:
C23H29N3O2
Mol. Mass.:
379.4953
SMILES:
O=C(NC1CCCCCC1)c1cc(nn(C2CCCC2)c1=O)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: