Reaction Details Report a problem with these data
Target
Steroid hormone receptor ERR2
Ligand
BDBM50233264
Substrate
n/a
Meas. Tech.
ChEMBL_1650379 (CHEMBL3999513)
IC50
300±n/a nM
Citation
 Yu, DD; Huss, JM; Li, H; Forman, BM Identification of novel inverse agonists of estrogen-related receptors ERR¿ and ERRß. Bioorg Med Chem 25:1585-1599 (2017) [PubMed]  Article 
Target
Name:
Steroid hormone receptor ERR2
Synonyms:
ERR beta-2 | ERR-beta | ERR2_HUMAN | ERRB2 | ESRL2 | ESRRB | Estrogen receptor-like 2 | Estrogen-related receptor beta | NR3B2 | Nuclear receptor subfamily 3 group B member 2 | Steroid hormone receptor ERR2 | Steroid hormone receptor ERR2 Beta
Type:
PROTEIN
Mol. Mass.:
48061.77
Organism:
Homo sapiens (Human)
Description:
ChEMBL_11254
Residue:
433
Sequence:
MSSDDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGLALGTHANGLDSPPMFAGAGLGGTPCRKSYEDCASGIMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRLDSESSPYLSLQISPPAKKPLTKIVSYLLVAEPDKLYAMPPPGMPEGDIKALTTLCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSAWMEILILGIVYRSLPYDDKLVYAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALALANSDSMYIEDLEAVQKLQDLLHEALQDYELSQRHEEPWRTGKLLLTLPLLRQTAAKAVQHFYSVKLQGKVPMHKLFLEMLEAKV
  
Inhibitor
Name:
BDBM50233264
Synonyms:
CHEMBL4085105
Type:
Small organic molecule
Emp. Form.:
C25H24O4
Mol. Mass.:
388.4557
SMILES:
[#6]-[#8]-[#6](=O)-[#6](-[#6])-[#6]\[#6](=[#6](/c1ccc(-[#8])cc1)-c1ccc(-[#8])cc1)-c1ccccc1
Structure:
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