Reaction Details Report a problem with these data
Target
Steroid hormone receptor ERR2
Ligand
BDBM50233272
Substrate
n/a
Meas. Tech.
ChEMBL_1650379 (CHEMBL3999513)
IC50
1100±n/a nM
Citation
 Yu, DD; Huss, JM; Li, H; Forman, BM Identification of novel inverse agonists of estrogen-related receptors ERR¿ and ERRß. Bioorg Med Chem 25:1585-1599 (2017) [PubMed]  Article 
Target
Name:
Steroid hormone receptor ERR2
Synonyms:
ERR beta-2 | ERR-beta | ERR2_HUMAN | ERRB2 | ESRL2 | ESRRB | Estrogen receptor-like 2 | Estrogen-related receptor beta | NR3B2 | Nuclear receptor subfamily 3 group B member 2 | Steroid hormone receptor ERR2 | Steroid hormone receptor ERR2 Beta
Type:
PROTEIN
Mol. Mass.:
48061.77
Organism:
Homo sapiens (Human)
Description:
ChEMBL_11254
Residue:
433
Sequence:
MSSDDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGLALGTHANGLDSPPMFAGAGLGGTPCRKSYEDCASGIMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRLDSESSPYLSLQISPPAKKPLTKIVSYLLVAEPDKLYAMPPPGMPEGDIKALTTLCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSAWMEILILGIVYRSLPYDDKLVYAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALALANSDSMYIEDLEAVQKLQDLLHEALQDYELSQRHEEPWRTGKLLLTLPLLRQTAAKAVQHFYSVKLQGKVPMHKLFLEMLEAKV
  
Inhibitor
Name:
BDBM50233272
Synonyms:
CHEMBL4064246
Type:
Small organic molecule
Emp. Form.:
C29H33NO4
Mol. Mass.:
459.5766
SMILES:
CN(C)CCOc1ccc(cc1)C(=C(\CCCO)c1ccccc1)\c1ccc(OC(C)=O)cc1
Structure:
Search PDB for entries with ligand similarity: