Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 2A
Ligand
BDBM50005251
Substrate
n/a
Meas. Tech.
ChEBML_1660344
Ki
211±n/a nM
Citation
 Glennon, RA The 2014 Philip S. Portoghese Medicinal Chemistry Lectureship: The"Phenylalkylaminome" with a Focus on Selected Drugs of Abuse. J Med Chem 60:2605-2628 (2017) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 2A
Synonyms:
5-HT-2 | 5-HT-2A | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT-2A) | 5-hydroxytryptamine receptor 2A (5HT-2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_HUMAN | HTR2 | HTR2A | Serotonin receptor 2A
Type:
undefined
Mol. Mass.:
52607.65
Organism:
Homo sapiens (Human)
Description:
P28223
Residue:
471
Sequence:
MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGCLSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV
  
Inhibitor
Name:
BDBM50005251
Synonyms:
(+/-)2-(2,5-Dimethoxy-phenyl)-1-methyl-ethylamine | 1-(2,5-dimethoxyphenyl)propan-2-amine | 2,5-dimethoxy-4-bromoamphetamine | 2-(2,5-Dimethoxy-phenyl)-1-methyl-ethylamine | 2-(2,5-Dimethoxy-phenyl)-1-methyl-ethylamine(2,5-DMA) | CHEMBL8642 | DMA
Type:
Small organic molecule
Emp. Form.:
C11H17NO2
Mol. Mass.:
195.2582
SMILES:
COc1ccc(OC)c(CC(C)N)c1
Structure:
Search PDB for entries with ligand similarity: