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Target
D(3) dopamine receptor
Ligand
BDBM50237348
Substrate
n/a
Meas. Tech.
ChEMBL_1661600 (CHEMBL4011212)
Ki
382±n/a nM
Citation
 Bonifazi, A; Yano, H; Ellenberger, MP; Muller, L; Kumar, V; Zou, MF; Cai, NS; Guerrero, AM; Woods, AS; Shi, L; Newman, AH Novel Bivalent Ligands Based on the Sumanirole Pharmacophore Reveal Dopamine D J Med Chem 60:2890-2907 (2017) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50237348
Synonyms:
CHEMBL4096422
Type:
Small organic molecule
Emp. Form.:
C24H28N4O3
Mol. Mass.:
420.5041
SMILES:
CN(CCCCOc1ccc2CCC(=O)Nc2c1)[C@@H]1Cc2cccc3[nH]c(=O)n(C1)c23 |r|
Structure:
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