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Target
P2Y purinoceptor 4
Ligand
BDBM50237557
Substrate
n/a
Meas. Tech.
ChEBML_1661636
IC50
2990±n/a nM
Citation
 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y Development of Potent and Selective Antagonists for the UTP-Activated P2Y J Med Chem 60:3020-3038 (2017) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 4
Synonyms:
NRU | P2P | P2RY4 | P2RY4_HUMAN | P2Y purinoceptor 4 | P2Y4 | Pyrimidinergic receptor P2Y4 | UNR | Uridine nucleotide receptor
Type:
PROTEIN
Mol. Mass.:
40977.17
Organism:
Homo sapiens (Human)
Description:
ChEMBL_751027
Residue:
365
Sequence:
MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL
  
Inhibitor
Name:
BDBM50237557
Synonyms:
CHEMBL4063945
Type:
Small organic molecule
Emp. Form.:
C23H19N2NaO5S
Mol. Mass.:
458.462
SMILES:
[Na+].CCCc1cccc(Nc2cc(c(N)c3C(=O)c4ccccc4C(=O)c23)S([O-])(=O)=O)c1
Structure:
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