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Target
Kappa-type opioid receptor
Ligand
BDBM50237594
Substrate
n/a
Meas. Tech.
ChEMBL_1661666 (CHEMBL4011278)
Ki
>1000±n/a nM
Citation
 Adamska-Bartlomiejczyk, A; Janecka, A; Szabó, MR; Cerlesi, MC; Calo, G; Kluczyk, A; Tömböly, C; Borics, A Cyclic mu-opioid receptor ligands containing multiple N-methylated amino acid residues. Bioorg Med Chem Lett 27:1644-1648 (2017) [PubMed]  Article 
Target
Name:
Kappa-type opioid receptor
Synonyms:
Kappa Opioid Receptor | OPIATE Kappa | OPRK1 | OPRK_CAVPO | Opiate Kappa 1 | mu/kappa opioid receptor
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42744.99
Organism:
Cavia porcellus (domestic guinea pig)
Description:
P41144
Residue:
380
Sequence:
MGRRRQGPAQPASELPARNACLLPNGSAWLPGWAEPDGNGSAGPQDEQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIILGGTKVREDVDIIECSLQFPDDDYSWWDLFMKICVFVFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFIICWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPIKMRMERQSTSRVRNTVQDPAYMRNVDGVNKPV
  
Inhibitor
Name:
BDBM50237594
Synonyms:
CHEMBL4087301
Type:
Small organic molecule
Emp. Form.:
C44H57N9O9
Mol. Mass.:
855.9783
SMILES:
CN[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CCCCNC(=O)C[C@H](NC(=O)CNC(=O)[C@H](Cc2ccccc2)N(C)C(=O)[C@H](Cc2ccccc2)N(C)C(=O)CNC1=O)C(N)=O |r|
Structure:
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