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Target
5-hydroxytryptamine receptor 1E
Ligand
BDBM50060417
Substrate
n/a
Ki
5011.87±n/a nM
Comments
PDSP_1663
Citation
 Kennett, GA; Wood, MD; Bright, F; Cilia, J; Piper, DC; Gager, T; Thomas, D; Baxter, GS; Forbes, IT; Ham, P; Blackburn, TP In vitro and in vivo profile of SB 206553, a potent 5-HT2C/5-HT2B receptor antagonist with anxiolytic-like properties. Br J Pharmacol 117:427-434 (1996) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 1E
Synonyms:
5-HT-1E | 5-HT1E | 5-Hydroxytryptamine Receptor Subtype 1E (5HT1E) | 5-hydroxytryptamine receptor 1E | 5-hydroxytryptamine receptor 1E (5-HT-1E) (S31) | 5-hydroxytryptamine receptor 1E (5-HT-1E) (Serotonin receptor 1E) (5-HT1E) (S31). | 5HT1E_HUMAN | HTR1E | S31 | Serotonin (5-HT) receptor | Serotonin 1e (5-HT1e) receptor | Serotonin Receptor 1E
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
41697.80
Organism:
Homo sapiens (Human)
Description:
gi_112822
Residue:
365
Sequence:
MNITNCTTEASMAIRPKTITEKMLICMTLVVITTLTTLLNLAVIMAIGTTKKLHQPANYLICSLAVTDLLVAVLVMPLSIIYIVMDRWKLGYFLCEVWLSVDMTCCTCSILHLCVIALDRYWAITNAIEYARKRTAKRAALMILTVWTISIFISMPPLFWRSHRRLSPPPSQCTIQHDHVIYTIYSTLGAFYIPLTLILILYYRIYHAAKSLYQKRGSSRHLSNRSTDSQNSFASCKLTQTFCVSDFSTSDPTTEFEKFHASIRIPPFDNDLDHPGERQQISSTRERKAARILGLILGAFILSWLPFFIKELIVGLSIYTVSSEVADFLTWLGYVNSLINPLLYTSFNEDFKLAFKKLIRCREHT
  
Inhibitor
Name:
BDBM50060417
Synonyms:
5-Methyl-3,5-dihydro-2H-pyrrolo[2,3-f]indole-1-carboxylic acid pyridin-3-ylamide | CHEMBL297784 | SB 206553 | SB-206553
Type:
Small organic molecule
Emp. Form.:
C17H16N4O
Mol. Mass.:
292.3351
SMILES:
Cn1ccc2cc3N(CCc3cc12)C(=O)Nc1cccnc1
Structure:
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