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Target
Beta-arrestin-1
Ligand
BDBM82479
Substrate
n/a
Ki
1000±n/a nM
Comments
PDSP_1408
Citation
 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding. Psychopharmacology (Berl) 124:57-73 (1996) [PubMed]  Article 
Target
Name:
Beta-arrestin-1
Synonyms:
ARRB1 | ARRB1_RABIT | Beta-arrestin-1 | Cholinergic, muscarinic | OPIATE Delta | PAF Platelet activating factor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
46360.54
Organism:
RABBIT
Description:
Cholinergic, muscarinic 0 RABBIT::Q95223
Residue:
410
Sequence:
MGDKGTRVFKKASPNGKLTVYLGKRGFVDHIDLVDPVDGVVLVDPEYLKERRVYVTLTCAFRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKKPLTRLQERLIKKLGEHAYPFTFEIPPKLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLEEKIHKRNSVRLVIRKVQYAPERPGPHPTAETTRLFLMSDKPLHLEASLDKEIYYHGEPIIVNVHVTNNTNKTVKKIKISVRQYADICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLTPFLANNREKRGLALDGKLKHEDTNLASSTLMREGANREILGIIVSYKVKVKLVVSRGGDVAVELPFTLMHPKPKEEPPHREVPENETPVDTNLIELDTNDDDIVFEDFARQRLKGMKDDKEEEDDVTGSPRLNDR
  
Inhibitor
Name:
BDBM82479
Synonyms:
CAS_132539-06-1 | NSC_4585 | OLANZAPINE | USRE49340, Rank 2
Type:
Small organic molecule
Emp. Form.:
C17H20N4S
Mol. Mass.:
312.432
SMILES:
CN1CCN(CC1)C1=c2cc(C)sc2=Nc2ccccc2N1 |c:8,15|
Structure:
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