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Target
Beta-arrestin-1
Ligand
BDBM50095890
Substrate
n/a
Ki
1000±n/a nM
Comments
PDSP_1571
Citation
 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding. Psychopharmacology (Berl) 124:57-73 (1996) [PubMed]  Article 
Target
Name:
Beta-arrestin-1
Synonyms:
ARRB1 | ARRB1_RABIT | Beta-arrestin-1 | Cholinergic, muscarinic | OPIATE Delta | PAF Platelet activating factor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
46360.54
Organism:
RABBIT
Description:
Cholinergic, muscarinic 0 RABBIT::Q95223
Residue:
410
Sequence:
MGDKGTRVFKKASPNGKLTVYLGKRGFVDHIDLVDPVDGVVLVDPEYLKERRVYVTLTCAFRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKKPLTRLQERLIKKLGEHAYPFTFEIPPKLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLEEKIHKRNSVRLVIRKVQYAPERPGPHPTAETTRLFLMSDKPLHLEASLDKEIYYHGEPIIVNVHVTNNTNKTVKKIKISVRQYADICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLTPFLANNREKRGLALDGKLKHEDTNLASSTLMREGANREILGIIVSYKVKVKLVVSRGGDVAVELPFTLMHPKPKEEPPHREVPENETPVDTNLIELDTNDDDIVFEDFARQRLKGMKDDKEEEDDVTGSPRLNDR
  
Inhibitor
Name:
BDBM50095890
Synonyms:
2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol | 2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethoxy]ethanol | CHEMBL716 | QUETIAPINE
Type:
Small organic molecule
Emp. Form.:
C21H25N3O2S
Mol. Mass.:
383.507
SMILES:
OCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12 |t:13|
Structure:
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