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Target
Protachykinin-1
Ligand
BDBM81483
Substrate
n/a
Ki
1000±n/a nM
Comments
PDSP_1499
Citation
 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding. Psychopharmacology (Berl) 124:57-73 (1996) [PubMed]  Article 
Target
Name:
Protachykinin-1
Synonyms:
NKA | NKNA | Protachykinin-1 | Substance P | TAC1 | TAC2 | TKN1_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
15006.99
Organism:
Homo sapiens (Human)
Description:
Substance P 0 HUMAN::P20366
Residue:
129
Sequence:
MKILVALAVFFLVSTQLFAEEIGANDDLNYWSDWYDSDQIKEELPEPFEHLLQRIARRPKPQQFFGLMGKRDADSSIEKQVALLKALYGHGQISHKRHKTDSFVGLMGKRALNSVAYERSAMQNYERRR
  
Inhibitor
Name:
BDBM81483
Synonyms:
CAS_1893-33-0 | NSC_4830 | PIPAMPERONE
Type:
Small organic molecule
Emp. Form.:
C21H30FN3O2
Mol. Mass.:
375.4802
SMILES:
NC(=O)C1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)N1CCCCC1
Structure:
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