Reaction Details Report a problem with these data
Target
D(2) dopamine receptor
Ligand
BDBM81484
Substrate
n/a
Ki
1.4±n/a nM
Comments
PDSP_428
Citation
 Creese, I; Burt, DR; Snyder, SH Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs. J Neuropsychiatry Clin Neurosci 8:223-6 (1996) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DRD2 | DRD2_BOVIN | Dopamine D2 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50698.79
Organism:
BOVINE
Description:
P20288
Residue:
444
Sequence:
MDPLNLSWYDDDPESRNWSRPFNGSEGKADRPPYNYYAMLLTLLIFVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPMLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRANLKAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKTVNPKIAKIFEIQSMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM81484
Synonyms:
BROMPERIDOL | Bromoperidol | CAS_2448 | NSC_2448
Type:
Small organic molecule
Emp. Form.:
C21H23BrFNO2
Mol. Mass.:
420.315
SMILES:
OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Br)cc1
Structure:
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