Reaction Details
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5-hydroxytryptamine receptor 3A
Ligand
BDBM86708
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_1954
Citation
Mos, J; Van Hest, A; Van Drimmelen, M; Herremans, AH; Olivier, B The putative 5-HT1A receptor antagonist DU125530 blocks the discriminative stimulus of the 5-HT1A receptor agonist flesinoxan in pigeons. Eur J Pharmacol 325:145-53 (1997) [PubMed] Article More Info.:
Target
Name:
5-hydroxytryptamine receptor 3A
Synonyms:
5-HT3 | HTR3A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
46633.35
Organism:
pigeon
Description:
5-HT3 HTR3A pigeon::A0A218UVI3
Residue:
407
Sequence:
MIGILFPAGAAPKYLCTYYDIVDYLNISSHDKLHTYILPKKDLQEPVEVTMDFFLVAILSVVEKLQTVSFYFVLNLEWQNPFATWNPRDFCNISEIVLPMDTYWSPPIFFLERVNGQNPELNYVVLMHNGSFNSTRPYQVTLTCSLIILKFPFDTQMCNLSVASFLYPVTDFVMKTRRTPAEIMEDSRSFILTDGEWKFTNLSIVEFTAMMDDKGFSVVTYVISMERRPTLYVLNLILPTCALYLLDMAVLFGPSSLEEKINFQIAIILGSSMLAVILNNSLPTSSNKPPIIVVFFLGTFLLMIMAVLDTFFLLYQQRKSLRLDKVLRSFQQDPQELPKRPMGTLAKGGPQLLPPPKKAQGQGQLTKRLWQLQELDPFLPVLEKVLLFSHLFLSLIFFTVVSIKWSS
Inhibitor
Name:
BDBM86708
Synonyms:
CAS_146714-97-8 | CHEMBL31354 | CHEMBL514874 | CHEMBL537403 | NSC_104911 | WAY 100,635
Type:
Small organic molecule
Emp. Form.:
C25H34N4O2
Mol. Mass.:
422.5631
SMILES:
COc1ccccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccn2)CC1
Structure:
