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Target
Alpha-1A adrenergic receptor
Ligand
BDBM50013019
Substrate
n/a
Ki
3630±n/a nM
Comments
PDSP_5
Citation
 Mos, J; Van Hest, A; Van Drimmelen, M; Herremans, AH; Olivier, B The putative 5-HT1A receptor antagonist DU125530 blocks the discriminative stimulus of the 5-HT1A receptor agonist flesinoxan in pigeons. Eur J Pharmacol 325:145-53 (1997) [PubMed]  Article 
Target
Name:
Alpha-1A adrenergic receptor
Synonyms:
adrenergic Alpha1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50699.64
Organism:
pigeon
Description:
adrenergic Alpha1 0 pigeon::A0A1V4KJJ8
Residue:
464
Sequence:
MAFLPGNSSDCSNCTHSVGPVNISKAILLGVILGGLIVFGVLGNILVILSVACHRHLQSVTHYYIINLAVADLLLTSTVLPFSATMEILGYWAFGRIFCNIWAAVDVLCCTASIMSLCIISIDRYIGVSYPLRYPSIVTEKRGLLALLCVWALSLVISIGPLFGWKEPAPEDETICQITEEPGYVLFSALGSFYLPLTIILVMYCRVYVVAKRENKGLSSGLKTERSHSEQVTLRIHRKNAPGASGSASNPKSKHHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFVVMPLGSFFPAVKPPDTLFKITFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRVQCLPRKQAAKKQSPSFNLNHPASPSTESSRGVVRIPVGSGETFYKISKSDGVCEWKIFSAVQSMPAKTAVSKDCTAAKVKSKGFLQECCCAGTSGNRGHENCKVPTIKIHTISLSESGEDV
  
Inhibitor
Name:
BDBM50013019
Synonyms:
(S)-7-(dipropylamino)-4-fluoro-5,6,7,8-tetrahydronaphthalen-1-ol | (S)-7-Dipropylamino-4-fluoro-5,6,7,8-tetrahydro-naphthalen-1-ol | (S)-UH-301 | 7-Dipropylamino-4-fluoro-5,6,7,8-tetrahydro-naphthalen-1-ol | 7-Dipropylamino-4-fluoro-5,6,7,8-tetrahydro-naphthalen-1-ol ((S)-UH301) | CHEMBL22778 | UH-301
Type:
Small organic molecule
Emp. Form.:
C16H24FNO
Mol. Mass.:
265.3663
SMILES:
CCCN(CCC)[C@H]1CCc2c(F)ccc(O)c2C1
Structure:
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