Reaction Details Report a problem with these data
Target
Leukotriene B4 receptor 2
Ligand
BDBM50037382
Substrate
n/a
Ki
1200±n/a nM
Comments
PDSP_3889
Citation
 Yokomizo, T; Izumi, T; Chang, K; Takuwa, Y; Shimizu, T A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis. Nature 387:620-4 (1997) [PubMed]  Article 
Target
Name:
Leukotriene B4 receptor 2
Synonyms:
BLT2R | BLTR2 | LT4R2_HUMAN | LTB4 receptor JULF2 | LTB4-R 2 | LTB4-R2 | LTB4R2 | LTB4R2 protein | Leukotriene B4 | Leukotriene B4 R2 | Leukotriene B4 receptor | Leukotriene B4 receptor 2 | Leukotriene B4 receptor BLT2 | Leukotriene b1 | Seven transmembrane receptor BLTR2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
37964.86
Organism:
Homo sapiens (Human)
Description:
Leukotriene 2 0 HUMAN::Q9NPC1
Residue:
358
Sequence:
MSVCYRPPGNETLLSWKTSRATGTAFLLLAALLGLPGNGFVVWSLAGWRPARGRPLAATLVLHLALADGAVLLLTPLFVAFLTRQAWPLGQAGCKAVYYVCALSMYASVLLTGLLSLQRCLAVTRPFLAPRLRSPALARRLLLAVWLAALLLAVPAAVYRHLWRDRVCQLCHPSPVHAAAHLSLETLTAFVLPFGLMLGCYSVTLARLRGARWGSGRHGARVGRLVSAIVLAFGLLWAPYHAVNLLQAVAALAPPEGALAKLGGAGQAARAGTTALAFFSSSVNPVLYVFTAGDLLPRAGPRFLTRLFEGSGEARGGGRSREGTMELRTTPQLKVVGQGRGNGDPGGGMEKDGPEWDL
  
Inhibitor
Name:
BDBM50037382
Synonyms:
5-{2-(2-Carboxy-ethyl)-3-[(E)-6-(4-methoxy-phenyl)-hex-5-enyloxy]-phenoxy}-pentanoic acid | 5-{2-(2-Carboxy-ethyl)-3-[6-(4-methoxy-phenyl)-hex-5-enyloxy]-phenoxy}-pentanoic acid (ONO-4057) | CHEMBL422420 | ONO 4057 | ONO-4057
Type:
Small organic molecule
Emp. Form.:
C27H34O7
Mol. Mass.:
470.5547
SMILES:
COc1ccc(\C=C\CCCCOc2cccc(OCCCCC(O)=O)c2CCC(O)=O)cc1
Structure:
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