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Target
D(3) dopamine receptor
Ligand
BDBM85097
Substrate
n/a
Ki
630.95±n/a nM
Comments
PDSP_1670
Citation
 Kennett, GA; Wood, MD; Bright, F; Trail, B; Riley, G; Holland, V; Avenell, KY; Stean, T; Upton, N; Bromidge, S; Forbes, IT; Brown, AM; Middlemiss, DN; Blackburn, TP SB 242084, a selective and brain penetrant 5-HT2C receptor antagonist. Neuropharmacology 36:609-20 (1997) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44279.64
Organism:
C.H.O.
Description:
DOPAMINE D3 DRD3 C.H.O.::A0A3Q0CXS4
Residue:
400
Sequence:
MAPLSQISNHINSTCGAENITGANRARPHAYYALSYCALILAIIFGNALVCAAVLRERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVQYQHGTGQSSCRRVTLMITAVWVLAFAVSCPLLFGFNTTGDPSICSISNPDFVIYSSVVSFYVPFGVTVLVYARIYMVLRQRRRKRILTRQNSQCVSIRPGFPQQPLSPGQTHGELKRYYSICQDTALRHPSFQGGGGGMSRVERTRNSLSPTMAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQACHVSPELYRATTWLGYVNSALNPVIYTTFNVEFRKAFLKILSC
  
Inhibitor
Name:
BDBM85097
Synonyms:
CAS_181632-25-7 | CHEMBL14563 | SB 242084
Type:
Small organic molecule
Emp. Form.:
C21H19ClN4O2
Mol. Mass.:
394.854
SMILES:
Cc1cc2CCN(C(=O)Nc3ccc(Oc4cccnc4C)nc3)c2cc1Cl
Structure:
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