Reaction Details Report a problem with these data
Target
Galanin receptor type 2
Ligand
BDBM85172
Substrate
n/a
Ki
0.7±n/a nM
Comments
PDSP_853
Citation
 Smith, KE; Forray, C; Walker, MW; Jones, KA; Tamm, JA; Bard, J; Branchek, TA; Linemeyer, DL; Gerald, C Expression cloning of a rat hypothalamic galanin receptor coupled to phosphoinositide turnover. J Biol Chem 272:24612-6 (1997) [PubMed]  Article 
Target
Name:
Galanin receptor type 2
Synonyms:
GALR2_RAT | Galanin R2 | Galanin receptor 2 | Galanin receptor type 2 | Galnr2 | Galr2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
40697.04
Organism:
RAT
Description:
Galanin R2 GALR2 RAT::O08726
Residue:
372
Sequence:
MNGSGSQGAENTSQEGGSGGWQPEAVLVPLFFALIFLVGTVGNALVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDDWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLALLFSGPYLSYYRQSQLANLTVCHPAWSAPRRRAMDLCTFVFSYLLPVLVLSLTYARTLRYLWRTVDPVTAGSGSQRAKRKVTRMIIIVAVLFCLCWMPHHALILCVWFGRFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRKICAGLLRPAPRRASGRVSILAPGNHSGSMLEQESTDLTQVSEAAGPLVPPPALPNCTASSRTLDPAC
  
Inhibitor
Name:
BDBM85172
Synonyms:
CAS_112747-70-3 | Galanin (1-15)
Type:
Small organic molecule
Emp. Form.:
C72H105N19O20
Mol. Mass.:
1556.7194
SMILES:
CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@H](C)O)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](C)C(O)=O
Structure:
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