Reaction Details
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Report a problem with these dataTarget
Somatostatin receptor type 5
Ligand
BDBM50063839
Substrate
n/a
Ki
3.4±n/a nM
Comments
PDSP_3365
Citation
Meyerhof, W The elucidation of somatostatin receptor functions: a current view. Rev Physiol Biochem Pharmacol 133:55-108 (1998) [PubMed] Article More Info.:
Target
Name:
Somatostatin receptor type 5
Synonyms:
SOMATOSTATIN SST5 | SSR5_RAT | Somatostatin receptor | Somatostatin receptor type 5 | Sstr5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
39986.50
Organism:
RAT
Description:
SOMATOSTATIN SST5 SSTR5 RAT::P30938
Residue:
363
Sequence:
MEPLSLASTPSWNASAASSGNHNWSLVGSASPMGARAVLVPVLYLLVCTVGLSGNTLVIYVVLRHAKMKTVTNVYILNLAVADVLFMLGLPFLATQNAVVSYWPFGSFLCRLVMTLDGINQFTSIFCLMVMSVDRYLAVVHPLRSARWRRPRVAKMASAAVWVFSLLMSLPLLVFADVQEGWGTCNLSWPEPVGLWGAAFITYTSVLGFFGPLLVICLCYLLIVVKVKAAGMRVGSSRRRRSEPKVTRMVVVVVLVFVGCWLPFFIVNIVNLAFTLPEEPTSAGLYFFVVVLSYANSCANPLLYGFLSDNFRQSFRKVLCLRRGYGMEDADAIEPRPDKSGRPQATLPTRSCEANGLMQTSRI
Inhibitor
Name:
BDBM50063839
Synonyms:
BIM 23268 | CHEMBL263606 | H-cyclo[DCys-Phe-Phe-DTrp-Lys-Thr-Phe-DCys]-NH2
Type:
Small organic molecule
Emp. Form.:
C54H67N11O9S2
Mol. Mass.:
1078.308
SMILES:
CC(O)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](N)CSSC[C@@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)C(N)=O
Structure:
