Reaction Details Report a problem with these data
Target
Beta-catenin-interacting protein 1
Ligand
BDBM269262
Substrate
n/a
Meas. Tech.
Idiopathic Pulmonary Fibrosis (IPF) Primary Screening Assay
IC50
247±n/a nM
Citation
 Hood, J; KC, SK; Wallace, DM 1H-pyrazolo[3,4-b]pyridines and therapeutic uses thereof US Patent  US10071086 Publication Date 9/11/2018 
Target
Name:
Beta-catenin-interacting protein 1
Synonyms:
CNBP1_HUMAN | CTNNBIP1 | ICAT | Inhibitor of beta-catenin and Tcf-4
Type:
Enzyme Catalytic Domain
Mol. Mass.:
9168.75
Organism:
Homo sapiens (Human)
Description:
Q9NSA3
Residue:
81
Sequence:
MNREGAPGKSPEEMYIQQKVRVLLMLRKMGSNLTASEEEFLRTYAGVVNSQLSQLPPHSIDQGAEDVVMAFSRSETEDRRQ
  
Inhibitor
Name:
BDBM269262
Synonyms:
US10071086, Compound 10
Type:
Small organic molecule
Emp. Form.:
C29H26FN9
Mol. Mass.:
519.5754
SMILES:
CN1CCN(Cc2cc(F)cc(c2)-c2cncc3[nH]c(nc23)-c2n[nH]c3ncc(cc23)-c2cccnc2)CC1
Structure:
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