Reaction Details Report a problem with these data
Target
Beta-catenin-interacting protein 1
Ligand
BDBM275495
Substrate
n/a
Meas. Tech.
Idiopathic Pulmonary Fibrosis (IPF) Primary Screening Assay
IC50
1090±n/a nM
Citation
 Hood, J; KC, SK; Wallace, DM 1H-pyrazolo[3,4-b]pyridines and therapeutic uses thereof US Patent  US10071086 Publication Date 9/11/2018 
Target
Name:
Beta-catenin-interacting protein 1
Synonyms:
CNBP1_HUMAN | CTNNBIP1 | ICAT | Inhibitor of beta-catenin and Tcf-4
Type:
Enzyme Catalytic Domain
Mol. Mass.:
9168.75
Organism:
Homo sapiens (Human)
Description:
Q9NSA3
Residue:
81
Sequence:
MNREGAPGKSPEEMYIQQKVRVLLMLRKMGSNLTASEEEFLRTYAGVVNSQLSQLPPHSIDQGAEDVVMAFSRSETEDRRQ
  
Inhibitor
Name:
BDBM275495
Synonyms:
US10071086, Compound 452
Type:
Small organic molecule
Emp. Form.:
C24H20N8S
Mol. Mass.:
452.534
SMILES:
CN(C)Cc1cncc(c1)-c1cnc2[nH]nc(-c3nc4c(cncc4[nH]3)-c3cccs3)c2c1
Structure:
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