Reaction Details Report a problem with these data
Target
Prostaglandin E2 receptor EP3 subtype
Ligand
BDBM50020300
Substrate
n/a
Ki
37±n/a nM
Comments
PDSP_1467
Citation
 Sharif, NA; Xu, SX; Williams, GW; Crider, JY; Griffin, BW; Davis, TL Pharmacology of [3H]prostaglandin E1/[3H]prostaglandin E2 and [3H]prostaglandin F2alpha binding to EP3 and FP prostaglandin receptor binding sites in bovine corpus luteum: characterization and correlation with functional data. J Pharmacol Exp Ther 286:1094-102 (1998) [PubMed] 
Target
Name:
Prostaglandin E2 receptor EP3 subtype
Synonyms:
PE2R3_BOVIN | PTGER3 | Prostaglandin E3
Type:
Enzyme Catalytic Domain
Mol. Mass.:
46379.75
Organism:
BOVINE
Description:
Prostaglandin E3 PTGER3 BOVINE::P34979
Residue:
417
Sequence:
MKATRDHASAPFCTRFNHSDPGIWAAERAVEAPNNLTLPPEPSEDCGSVSVAFSMTMMITGFVGNALAITLVSKSYRRREGKRKKSFLLCIGWLALTDMVGQLLTSPVVIVLYLSHQRWEQLDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALATRAPHWYSSHMKTSVTRAVLLGVWLAVLAFALLPVLGVGQYTIQWPGTWCFISTGPGGNGTNSRQNWGNVFFASAFAILGLSALVVTFACNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLIMMLKMIFNHTSVEHCKTYTENQDECNFFLIAVRLASLNQILDPWVYLLLRKILLQKFCQLLKGHSYGLDTEGGTENKDKEMKENLYISNLSRFFILLGHFTEARRGRGHIYLHTLEHQ
  
Inhibitor
Name:
BDBM50020300
Synonyms:
(S-isomer)7-[3,5-Dihydroxy-2-(3-hydroxy-oct-1-enyl)-cyclopentyl]-hept-5-enoic acid | (Z)-7-[(1R,3R,5S)-3,5-Dihydroxy-2-((E)-(S)-3-hydroxy-oct-1-enyl)-cyclopentyl]-hept-5-enoic acid | 7-[3,5-Dihydroxy-2-(3-hydroxy-oct-1-enyl)-cyclopentyl]-hept-5-enoic acid | CHEMBL12114 | PGF2Alpha | Prostaglandin F2alpha7-[3,5-Dihydroxy-2-(3-hydroxy-oct-1-enyl)-cyclopentyl]-hept-5-enoic acid
Type:
Small organic molecule
Emp. Form.:
C20H34O5
Mol. Mass.:
354.481
SMILES:
CCCCC[C@H](O)\C=C\C1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O
Structure:
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