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Target
Prostaglandin F2-alpha receptor
Ligand
BDBM85183
Substrate
n/a
Ki
2500±n/a nM
Comments
PDSP_1786
Citation
 Sharif, NA; Xu, SX; Williams, GW; Crider, JY; Griffin, BW; Davis, TL Pharmacology of [3H]prostaglandin E1/[3H]prostaglandin E2 and [3H]prostaglandin F2alpha binding to EP3 and FP prostaglandin receptor binding sites in bovine corpus luteum: characterization and correlation with functional data. J Pharmacol Exp Ther 286:1094-102 (1998) [PubMed] 
Target
Name:
Prostaglandin F2-alpha receptor
Synonyms:
PF2R_BOVIN | PGF receptor | PGF2 alpha receptor | PTGFR | ProstaglandinF2Alpha | Prostanoid FP receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41044.75
Organism:
BOVINE
Description:
ProstaglandinF2Alpha PTGFR BOVINE::P37289
Residue:
362
Sequence:
MSTNSSIQPVSPESELLSNTTCQLEEDLSISFSIIFMTVGILSNSLAIAILMKAYQRFRQKYKSSFLLLASALVITDFFGHLINGTIAVFVYASDKDWIYFDKSNILCSIFGICMVFSGLCPLFLGSLMAIERCIGVTKPIFHSTKITTKHVKMMLSGVCFFAVFVALLPILGHRDYKIQASRTWCFYKTDEIKDWEDRFYLLLFAFLGLLALGISFVCNAITGISLLKVKFRSQQHRQGRSHHFEMVIQLLGIMCVSCICWSPFLVTMASIGMNIQDFKDSCERTLFTLRMATWNQILDPWVYILLRKAVLRNLYVCTRRCCGVHVISLHVWELSSIKDSLKVAAISDLPVTEKVTQQTST
  
Inhibitor
Name:
BDBM85183
Synonyms:
CAS_60325-46-4 | NSC_43251 | SULPROSTONE
Type:
Small organic molecule
Emp. Form.:
C23H31NO7S
Mol. Mass.:
465.56
SMILES:
CS(=O)(=O)NC(=O)CCCC=CCC1C(C=CC(O)COc2ccccc2)C(O)CC1=O |w:10.9,15.14|
Structure:
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