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Target
Melatonin receptor type 1A
Ligand
BDBM50034101
Substrate
n/a
Ki
199.52±n/a nM
Comments
PDSP_1296
Citation
 Spadoni, G; Balsamini, C; Bedini, A; Diamantini, G; Di Giacomo, B; Tontini, A; Tarzia, G; Mor, M; Plazzi, PV; Rivara, S; Nonno, R; Pannacci, M; Lucini, V; Fraschini, F; Stankov, BM 2-[N-Acylamino(C1-C3)alkyl]indoles as MT1 melatonin receptor partial agonists, antagonists, and putative inverse agonists. J Med Chem 41:3624-34 (1998) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1A
Synonyms:
MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A
Type:
Enzyme
Mol. Mass.:
39392.94
Organism:
Homo sapiens (Human)
Description:
P48039
Residue:
350
Sequence:
MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
  
Inhibitor
Name:
BDBM50034101
Synonyms:
CHEMBL14701 | Compound 6 | Cyclobutanecarboxylic acid [2-(2-phenyl-1H-indol-3-yl)-ethyl]-amide | N-CBCPT
Type:
Small organic molecule
Emp. Form.:
C21H22N2O
Mol. Mass.:
318.4122
SMILES:
O=C(NCCc1c([nH]c2ccccc12)-c1ccccc1)C1CCC1
Structure:
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