Reaction Details
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Report a problem with these dataTarget
Muscarinic acetylcholine receptor M4
Ligand
BDBM82376
Substrate
n/a
Ki
5.88±n/a nM
Comments
PDSP_1795
Citation
Chelala, JL; Kilani, A; Miller, MJ; Martin, RJ; Ernsberger, P Muscarinic receptor binding sites of the M4 subtype in porcine lung parenchyma. Pharmacol Toxicol 83:200-7 (1998) [PubMed] Article More Info.:
Target
Name:
Muscarinic acetylcholine receptor M4
Synonyms:
CHRM4 | CHRM4 protein | Cholinergic, muscarinic M4
Type:
Enzyme Catalytic Domain
Mol. Mass.:
30028.84
Organism:
bovine
Description:
A6QQE4
Residue:
271
Sequence:
MTVLYVHISLASRSRVHKHRPEGPKEKKAKTLAFLKSPLMKQSVKKPPPPGDTTARGELRNGKLEEAPPPVLPPPPRPMADKDTSNESSSGSATQNTKERPPTELSTTEATTPATPAPPLQPRTLNPASKWSKIQIVTKQTGNECVTAIEIVPATPAGMRPAANVARKFASIARSQVRKKRQMAARERKVTRTIFAILLAFILTWTPYNVMVLVNTFCQSCIPETVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYRNIGTAR
Inhibitor
Name:
BDBM82376
Synonyms:
CAS_80880-90-6 | NSC_5387 | TELENZEPINE
Type:
Small organic molecule
Emp. Form.:
C19H22N4O2S
Mol. Mass.:
370.469
SMILES:
CN1CCN(CC(=O)N2c3c(C)scc3C(=O)Nc3ccccc23)CC1
Structure:
