Reaction Details Report a problem with these data
Target
Hrh3 protein
Ligand
BDBM50070220
Substrate
n/a
Ki
0.95±n/a nM
Comments
PDSP_907
Citation
 Yates, SL; Phillips, JG; Gregory, R; Pawlowski, GP; Fadnis, L; Khan, MA; Ali, SM; Tedford, CE Identification and pharmacological characterization of a series of new 1H-4-substituted-imidazoyl histamine H3 receptor ligands. J Pharmacol Exp Ther 289:1151-9 (1999) [PubMed] 
Target
Name:
Hrh3 protein
Synonyms:
HISTAMINE H3 | HRH3 | Hrh3 protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
37860.96
Organism:
RAT
Description:
Q5PPG3
Residue:
344
Sequence:
MERAPPDGLMNASGTLAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGRCIPDY
  
Inhibitor
Name:
BDBM50070220
Synonyms:
4-(6-Cyclopentyl-hex-3-ynyl)-1H-imidazole | CHEMBL274977 | GT 2286
Type:
Small organic molecule
Emp. Form.:
C14H20N2
Mol. Mass.:
216.322
SMILES:
C(CC1CCCC1)C#CCCc1cnc[nH]1
Structure:
Search PDB for entries with ligand similarity: