Reaction Details Report a problem with these data
Target
Alpha-2C adrenergic receptor
Ligand
BDBM82548
Substrate
n/a
Ki
12±n/a nM
Comments
PDSP_4623
Citation
 Sánchez, C; Hyttel, J Comparison of the effects of antidepressants and their metabolites on reuptake of biogenic amines and on receptor binding. Cell Mol Neurobiol 19:467-89 (1999) [PubMed]  Article 
Target
Name:
Alpha-2C adrenergic receptor
Synonyms:
ADA2C_RAT | Adra2c | Adrenergic receptor alpha | Alpha-2C adrenergic receptor | adrenergic Alpha2 | adrenergic Alpha2C
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49890.50
Organism:
RAT
Description:
adrenergic Alpha2 0 RAT::P22086
Residue:
458
Sequence:
MASPALAAALAAAAAEGPNGSDAGEWGSGGGANASGTDWGPPPGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSFYRRPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRGPAGPDGASPTTENGLGKAAGENGHCAPPRTEVEPDESSAAERRRRRGALRRGGRRREGAEGDTGSADGPGPGLAAEQGARTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQLPEPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ
  
Inhibitor
Name:
BDBM82548
Synonyms:
CAS_897-15-4 | Dothiepin | NSC_3155
Type:
Small organic molecule
Emp. Form.:
C19H21NS
Mol. Mass.:
295.442
SMILES:
CN(C)CCC=C1c2ccccc2CSc2ccccc12 |w:5.4|
Structure:
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