Reaction Details
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Solute carrier organic anion transporter family member 2A1
Ligand
BDBM82213
Substrate
n/a
Ki
6602±n/a nM
Comments
PDSP_1458
Citation
Abramovitz, M; Adam, M; Boie, Y; Carrière, M; Denis, D; Godbout, C; Lamontagne, S; Rochette, C; Sawyer, N; Tremblay, NM; Belley, M; Gallant, M; Dufresne, C; Gareau, Y; Ruel, R; Juteau, H; Labelle, M; Ouimet, N; Metters, KM The utilization of recombinant prostanoid receptors to determine the affinities and selectivities of prostaglandins and related analogs. Biochim Biophys Acta 1483:285-93 (2000) [PubMed] Article More Info.:
Target
Name:
Solute carrier organic anion transporter family member 2A1
Synonyms:
OATP2A1 | Prostaglandin Transporter | SLC21A2 | SLCO2A1 | SO2A1_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
70068.67
Organism:
Homo sapiens (Human)
Description:
Prostaglandin Transporter 0 HUMAN::Q92959
Residue:
643
Sequence:
MGLLPKLGASQGSDTSTSRAGRCARSVFGNIKVFVLCQGLLQLCQLLYSAYFKSSLTTIEKRFGLSSSSSGLISSLNEISNAILIIFVSYFGSRVHRPRLIGIGGLFLAAGAFILTLPHFLSEPYQYTLASTGNNSRLQAELCQKHWQDLPPSKCHSTTQNPQKETSSMWGLMVVAQLLAGIGTVPIQPFGISYVDDFSEPSNSPLYISILFAISVFGPAFGYLLGSVMLQIFVDYGRVNTAAVNLVPGDPRWIGAWWLGLLISSALLVLTSFPFFFFPRAMPIGAKRAPATADEARKLEEAKSRGSLVDFIKRFPCIFLRLLMNSLFVLVVLAQCTFSSVIAGLSTFLNKFLEKQYGTSAAYANFLIGAVNLPAAALGMLFGGILMKRFVFSLQAIPRIATTIITISMILCVPLFFMGCSTPTVAEVYPPSTSSSIHPQSPACRRDCSCPDSIFHPVCGDNGIEYLSPCHAGCSNINMSSATSKQLIYLNCSCVTGGSASAKTGSCPVPCAHFLLPAIFLISFVSLIACISHNPLYMMVLRVVNQEEKSFAIGVQFLLMRLLAWLPSPALYGLTIDHSCIRWNSLCLGRRGACAYYDNDALRDRYLGLQMGYKALGMLLLCFISWRVKKNKEYNVQKAAGLI
Inhibitor
Name:
BDBM82213
Synonyms:
CAS_41598-07-6 | NSC_114678 | PGD2
Type:
Small organic molecule
Emp. Form.:
C20H30O4
Mol. Mass.:
334.4498
SMILES:
CCCCCC(O)CC=C1C(CC=CCCCC(O)=O)C=CC1=O |w:8.7,12.11,c:20|
Structure:
