Reaction Details Report a problem with these data
Target
Nicotinic acetylcholine receptor
Ligand
BDBM81888
Substrate
n/a
Ki
730±n/a nM
Comments
PDSP_593
Citation
 Mukhin, AG; Gündisch, D; Horti, AG; Koren, AO; Tamagnan, G; Kimes, AS; Chambers, J; Vaupel, DB; King, SL; Picciotto, MR; Innis, RB; London, ED 5-Iodo-A-85380, an alpha4beta2 subtype-selective ligand for nicotinic acetylcholine receptors. Mol Pharmacol 57:642-9 (2000) [PubMed]  Article 
Target
Name:
Nicotinic acetylcholine receptor
Synonyms:
Nicotinic acetylcholine receptor | n-AChR
Type:
Enzyme Catalytic Domain
Mol. Mass.:
2478.99
Organism:
RAT
Description:
n-AChR 0 RAT::Q62594
Residue:
23
Sequence:
MTMALLGTLLLLALFGRSQGKNE
  
Inhibitor
Name:
BDBM81888
Synonyms:
CAS_8063-06-7 | Curare | NSC_411885
Type:
Small organic molecule
Emp. Form.:
C38H44N2O6
Mol. Mass.:
624.7647
SMILES:
COc1cc2CC[N+](C)(C)C3Cc4ccc(O)c(Oc5cc6C(Cc7ccc(Oc(c1O)c23)cc7)[N+](C)(C)CCc6cc5OC)c4
Structure:
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