Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 2C
Ligand
BDBM82088
Substrate
n/a
Ki
7.94±n/a nM
Comments
PDSP_1505
Citation
 Glusa, E; Pertz, HH Further evidence that 5-HT-induced relaxation of pig pulmonary artery is mediated by endothelial 5-HT(2B) receptors. Br J Pharmacol 130:692-8 (2000) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 2C
Synonyms:
5-HT2C | HTR2C
Type:
Enzyme Catalytic Domain
Mol. Mass.:
51519.58
Organism:
PIG
Description:
G7ZKZ7
Residue:
457
Sequence:
MVNLRKAVHSFLVHLIGLLVWQCDISVSPVAAIVTDIFNTSDGGRFKFPDGVQNWPALSIVIIIILTIGGNILVIMAVSLEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAVRGPVEHSRFNSRTKAIMKIAIVWAISLGVSVPIPVIGLRDEDKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYCLTIHVLRRQALMLLRGHTEEPPGISLDFLKCCKRNTDEESAANPNQDLNPRRRKKKERRPRGTMQAINNERKASKVLGIVFFVFLIMWCPFFITNILSVLCGKACNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKVYRRAFSNYLRCNYKADKKPPIRQIPRVAATALSGRELNVNIYRHTNEPVIKKADDNEPGIEMQVENLELPVNPSNVVSERISSV
  
Inhibitor
Name:
BDBM82088
Synonyms:
CAS_15574-96-6 | NSC_27400 | PIZOTIFEN
Type:
Small organic molecule
Emp. Form.:
C19H21NS
Mol. Mass.:
295.442
SMILES:
[#6]-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1/c2ccsc2-[#6]-[#6]-c2ccccc-12
Structure:
Search PDB for entries with ligand similarity: