Reaction Details Report a problem with these data
Target
Glutamate receptor 3
Ligand
BDBM50089910
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_2023
Citation
 Wright, RA; Arnold, MB; Wheeler, WJ; Ornstein, PL; Schoepp, DD [3H]LY341495 binding to group II metabotropic glutamate receptors in rat brain. J Pharmacol Exp Ther 298:453-60 (2001) [PubMed] 
Target
Name:
Glutamate receptor 3
Synonyms:
GRIA3_RAT | Glur3 | Glutamate receptor 3 | Glutamate receptor ionotropic, AMPA 3 | Glutamate-AMPA | Gria3
Type:
Enzyme Catalytic Domain
Mol. Mass.:
100383.57
Organism:
RAT
Description:
Glutamate-AMPA GRIA3 RAT::P19492
Residue:
888
Sequence:
MGQSVLRAVFFLVLGLLGHSHGGFPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFHLNYHVDHLDSSNSFSVTNAFCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSFPTDADVQFVIQMRPALKGAILSLLSYYKWEKFVYLYDTERGFSVLQAIMEAAVQNNWQVTARSVGNIKDVQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYMLANLGFTDILLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKNAPLKYTSALTHDAILVIAEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQGMTGNIQFDTYGRRTNYTIDVYEMKVSGSRKAGYWNEYERFVPFSDQQISNDSSSSENRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFCYKSRAESKRMKLTKNTQNFKPAPATNTQNYATYREGYNVYGTESVKI
  
Inhibitor
Name:
BDBM50089910
Synonyms:
2-Amino-2-(4-phosphono-phenyl)-propionic acid | 2-Amino-2-(4-phosphono-phenyl)-propionic acid(RS-MPPG) | CHEMBL86508 | MPPG
Type:
Small organic molecule
Emp. Form.:
C9H12NO5P
Mol. Mass.:
245.169
SMILES:
CC(N)(C(O)=O)c1ccc(cc1)P(O)(O)=O
Structure:
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