Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 1
Ligand
BDBM50024210
Substrate
n/a
Ki
1084±n/a nM
Comments
PDSP_1920
Citation
 Borowsky, B; Adham, N; Jones, KA; Raddatz, R; Artymyshyn, R; Ogozalek, KL; Durkin, MM; Lakhlani, PP; Bonini, JA; Pathirana, S; Boyle, N; Pu, X; Kouranova, E; Lichtblau, H; Ochoa, FY; Branchek, TA; Gerald, C Trace amines: identification of a family of mammalian G protein-coupled receptors. Proc Natl Acad Sci U S A 98:8966-71 (2001) [PubMed]  Article 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TA1 | TAAR1 | TAAR1_HUMAN | TAR1 | TRAR1 | trace amine-associated receptor 1
Type:
PROTEIN
Mol. Mass.:
39107.47
Organism:
Homo sapiens (Human)
Description:
ChEMBL_792734
Residue:
339
Sequence:
MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNWLIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRGGCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQIGLEMKNGISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFNPMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS
  
Inhibitor
Name:
BDBM50024210
Synonyms:
1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanamine | 2-(3-indolyl)ethylamine | CHEMBL6640 | tryptamine
Type:
Small organic molecule
Emp. Form.:
C10H12N2
Mol. Mass.:
160.2157
SMILES:
NCCc1c[nH]c2ccccc12
Structure:
Search PDB for entries with ligand similarity: