Reaction Details Report a problem with these data
Target
Delta-type opioid receptor
Ligand
BDBM50333880
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_3174
Citation
 Butterweck, V; Nahrstedt, A; Evans, J; Hufeisen, S; Rauser, L; Savage, J; Popadak, B; Ernsberger, P; Roth, BL In vitro receptor screening of pure constituents of St. John's wort reveals novel interactions with a number of GPCRs. Psychopharmacology (Berl) 162:193-202 (2002) [PubMed]  Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
Delta opioid receptor | Delta-type opioid receptor | OPIATE Delta | OPRD1 | OPRD_PIG
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25736.90
Organism:
GUINEA PIG
Description:
OPIATE Delta OPRD1 GUINEA PIG::P79291
Residue:
228
Sequence:
GIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILVITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
  
Inhibitor
Name:
BDBM50333880
Synonyms:
CHEMBL1614664 | Hypericin | Pseudohypericin
Type:
Small organic molecule
Emp. Form.:
C30H16O9
Mol. Mass.:
520.4426
SMILES:
Cc1cc(O)c2c3c1c1c(CO)cc(O)c4c1c1c5c(c(O)cc(O)c5c4=O)c4c(O)cc(O)c(c4c31)c2=O
Structure:
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